The effects of the Histone Deacetylase (HDAC) Inhibitor 4-Phenylbutyrate on gap junction conductance and permeability

• Päätekijät: Joshua eKaufman (Tekijä), Chris eGordon (Tekijä), Roberto eBergamaschi (Tekijä), Hong Zhan Wang (Tekijä), Ira S Cohen (Tekijä), Virginijus eValiunas (Tekijä), Peter eBrink (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2013-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Longitudinal resistance is a key factor in determining cardiac action potential propagation. Action potential conduction velocity has been shown to be proportional to the square root of longitudinal resistance. A major determinant of longitudinal resistance in myocardium is the gap junction channel,...