Cathepsin K activity controls cachexia‐induced muscle atrophy via the modulation of IRS1 ubiquitination

• मुख्य लेखकों: Xiangkun Meng (लेखक), Zhe Huang (लेखक), Aiko Inoue (लेखक), Hailong Wang (लेखक), Ying Wan (लेखक), Xueling Yue (लेखक), Shengnan Xu (लेखक), Xueying Jin (लेखक), Guo‐Ping Shi (लेखक), Masafumi Kuzuya (लेखक), Xian Wu Cheng (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2022-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Cachexia is a complicated metabolic disorder that is characterize by progressive atrophy of skeletal muscle. Cathepsin K (CTSK) is a widely expressed cysteine protease that has garnered attention because of its enzymatic and non‐enzymatic functions in signalling in various pathol...