Mice deficient in H+-ATPase a4 subunit have severe hearing impairment associated with enlarged endolymphatic compartments within the inner ear

SUMMARY Mutations in the ATP6V0A4 gene lead to autosomal recessive distal renal tubular acidosis in patients, who often show sensorineural hearing impairment. A first Atp6v0a4 knockout mouse model that recapitulates the loss of H+-ATPase function seen in humans has been generated and recently report...

Full description

Saved in:
Bibliographic Details
Main Authors: Beatriz Lorente-Cánovas (Author), Neil Ingham (Author), Elizabeth E. Norgett (Author), Zoe J. Golder (Author), Fiona E. Karet Frankl (Author), Karen P. Steel (Author)
Format: Book
Published: The Company of Biologists, 2013-03-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available