Mice deficient in H+-ATPase a4 subunit have severe hearing impairment associated with enlarged endolymphatic compartments within the inner ear

SUMMARY Mutations in the ATP6V0A4 gene lead to autosomal recessive distal renal tubular acidosis in patients, who often show sensorineural hearing impairment. A first Atp6v0a4 knockout mouse model that recapitulates the loss of H+-ATPase function seen in humans has been generated and recently report...

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ग्रंथसूची विवरण
मुख्य लेखकों: Beatriz Lorente-Cánovas (लेखक), Neil Ingham (लेखक), Elizabeth E. Norgett (लेखक), Zoe J. Golder (लेखक), Fiona E. Karet Frankl (लेखक), Karen P. Steel (लेखक)
स्वरूप: पुस्तक
प्रकाशित: The Company of Biologists, 2013-03-01T00:00:00Z.
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