High-capacity adenovector delivery of forced CRISPR-Cas9 heterodimers fosters precise chromosomal deletions in human cells
Genome editing based on dual CRISPR-Cas9 complexes (multiplexes) permits removing specific genomic sequences in living cells leveraging research on functional genomics and genetic therapies. Delivering the required large and multicomponent reagents in a synchronous and stoichiometric manner remains,...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2023-03-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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