Cover Image

Semi-PBPK Modeling and Simulation to Evaluate the Local and Systemic Pharmacokinetics of OC-01(Varenicline) Nasal Spray

This study aimed to build a nasal semi-physiologically based pharmacokinetic (PBPK) model to predict the intranasal pharmacokinetic (PK) of the OC-01(varenicline) nasal spray and accelerate the development of this drug. Based on the physiology of the human upper respiratory system, the semi-PBPK mod...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaofei Wu (Author), Fan Zhang (Author), Mengyang Yu (Author), Faming Ding (Author), Jinghui Luo (Author), Bo Liu (Author), Yuan Li (Author), Zhiping Li (Author), Hongyun Wang (Author)
Format: Book
Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items