Development of Novel ROCK Inhibitors via 3D-QSAR and Molecular Docking Studies: A Framework for Multi-Target Drug Design
<b>Background/Objectives:</b> Alterations in the actin cytoskeleton correlates to tumor progression and affect critical cellular processes such as adhesion, migration and invasion. Rho-associated coiled-coil-containing protein kinases (ROCK1 and ROCK2), important regulators of the actin...
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Main Authors: | Milan Beljkas (Author), Milos Petkovic (Author), Ana Vuletic (Author), Ana Djuric (Author), Juan Francisco Santibanez (Author), Tatjana Srdic-Rajic (Author), Katarina Nikolic (Author), Slavica Oljacic (Author) |
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Format: | Book |
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MDPI AG,
2024-09-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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