Protective Effect of GIP against Monosodium Glutamate-Induced Ferroptosis in Mouse Hippocampal HT-22 Cells through the MAPK Signaling Pathway

• Päätekijät: Jiwon Ko (Tekijä), Soyoung Jang (Tekijä), Wookbong Kwon (Tekijä), Si-Yong Kim (Tekijä), Soyeon Jang (Tekijä), Eungyung Kim (Tekijä), Young-Rae Ji (Tekijä), Sijun Park (Tekijä), Myoung-Ok Kim (Tekijä), Seong-Kyoon Choi (Tekijä), Dong-Hyung Cho (Tekijä), Hyun-Shik Lee (Tekijä), Su-Geun Lim (Tekijä), Zae-Young Ryoo (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

The effect of glucose-dependent insulinotropic polypeptide (GIP) on cells under oxidative stress induced by glutamate, a neurotransmitter, and the underlying molecular mechanisms were assessed in the present study. We found that in the pre-treatment of HT-22 cells with glutamate in a dose-dependent...