Protective Effect of GIP against Monosodium Glutamate-Induced Ferroptosis in Mouse Hippocampal HT-22 Cells through the MAPK Signaling Pathway

• 主要な著者: Jiwon Ko (著者), Soyoung Jang (著者), Wookbong Kwon (著者), Si-Yong Kim (著者), Soyeon Jang (著者), Eungyung Kim (著者), Young-Rae Ji (著者), Sijun Park (著者), Myoung-Ok Kim (著者), Seong-Kyoon Choi (著者), Dong-Hyung Cho (著者), Hyun-Shik Lee (著者), Su-Geun Lim (著者), Zae-Young Ryoo (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The effect of glucose-dependent insulinotropic polypeptide (GIP) on cells under oxidative stress induced by glutamate, a neurotransmitter, and the underlying molecular mechanisms were assessed in the present study. We found that in the pre-treatment of HT-22 cells with glutamate in a dose-dependent...