Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils.

• Үндсэн зохиолчид: Bin Zhan (Зохиогч), Sridhar Arumugam (Зохиогч), Malcolm W Kennedy (Зохиогч), Nancy Tricoche (Зохиогч), Lu-Yun Lian (Зохиогч), Oluwatoyin A Asojo (Зохиогч), Sasisekhar Bennuru (Зохиогч), Maria Elena Bottazzi (Зохиогч), Peter J Hotez (Зохиогч), Sara Lustigman (Зохиогч), Thomas R Klei (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Public Library of Science (PLoS), 2018-10-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Parasitic nematodes produce an unusual class of fatty acid and retinol (FAR)-binding proteins that may scavenge host fatty acids and retinoids. Two FARs from Brugia malayi (Bm-FAR-1 and Bm-FAR-2) were expressed as recombinant proteins, and their ligand binding, structural characteristics, and immuno...