Long-Term Follow-Up and Optimization of Interleukin-1 Inhibitors in the Management of Monogenic Autoinflammatory Diseases: Real-Life Data from the JIR Cohort

• Main Authors: Véronique Hentgen (Author), Isabelle Koné-Paut (Author), Alexandre Belot (Author), Caroline Galeotti (Author), Gilles Grateau (Author), Aurelia Carbasse (Author), Anne Pagnier (Author), Pascal Pillet (Author), Marc Delord (Author), Michael Hofer (Author), Sophie Georgin-Lavialle (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: The major role of interleukin (IL)-1 in the pathogenesis of hereditary recurrent fever syndromes favored the employment of targeted therapies modulating IL-1 signaling. However the best use of IL1 inhibitors in terms of dosage is difficult to define at present.Methods: In order to better...