Long-Term Follow-Up and Optimization of Interleukin-1 Inhibitors in the Management of Monogenic Autoinflammatory Diseases: Real-Life Data from the JIR Cohort

• Autores principales: Véronique Hentgen (Autor), Isabelle Koné-Paut (Autor), Alexandre Belot (Autor), Caroline Galeotti (Autor), Gilles Grateau (Autor), Aurelia Carbasse (Autor), Anne Pagnier (Autor), Pascal Pillet (Autor), Marc Delord (Autor), Michael Hofer (Autor), Sophie Georgin-Lavialle (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Objectives: The major role of interleukin (IL)-1 in the pathogenesis of hereditary recurrent fever syndromes favored the employment of targeted therapies modulating IL-1 signaling. However the best use of IL1 inhibitors in terms of dosage is difficult to define at present.Methods: In order to better...