MicroRNA Sequencing Analysis in Obstructive Sleep Apnea and Depression: Anti-Oxidant and MAOA-Inhibiting Effects of miR-15b-5p and miR-92b-3p through Targeting PTGS1-NF-κB-SP1 Signaling

• Egile Nagusiak: Yung-Che Chen (Egilea), Po-Yuan Hsu (Egilea), Mao-Chang Su (Egilea), Ting-Wen Chen (Egilea), Chang-Chun Hsiao (Egilea), Chien-Hung Chin (Egilea), Chia-Wei Liou (Egilea), Po-Wen Wang (Egilea), Ting-Ya Wang (Egilea), Yong-Yong Lin (Egilea), Chiu-Ping Lee (Egilea), Meng-Chih Lin (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2021-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The aim of this study was to identify novel microRNAs related to obstructive sleep apnea (OSA) characterized by intermittent hypoxia with re-oxygenation (IHR) injury. Illumina MiSeq was used to identify OSA-associated microRNAs, which were validated in an independent cohort. The interaction between...