MicroRNA Sequencing Analysis in Obstructive Sleep Apnea and Depression: Anti-Oxidant and MAOA-Inhibiting Effects of miR-15b-5p and miR-92b-3p through Targeting PTGS1-NF-κB-SP1 Signaling

• Main Authors: Yung-Che Chen (Author), Po-Yuan Hsu (Author), Mao-Chang Su (Author), Ting-Wen Chen (Author), Chang-Chun Hsiao (Author), Chien-Hung Chin (Author), Chia-Wei Liou (Author), Po-Wen Wang (Author), Ting-Ya Wang (Author), Yong-Yong Lin (Author), Chiu-Ping Lee (Author), Meng-Chih Lin (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to identify novel microRNAs related to obstructive sleep apnea (OSA) characterized by intermittent hypoxia with re-oxygenation (IHR) injury. Illumina MiSeq was used to identify OSA-associated microRNAs, which were validated in an independent cohort. The interaction between...