Berberine prevents lethal EV71 neurological infection in newborn mice

• Main Authors: Guangyi Cui (Author), Han Wang (Author), Chongting Yang (Author), Xiaoxiao Zhou (Author), Junyi Wang (Author), Tong Wang (Author), Tonghui Ma (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Enterovirus 71 (EV71) is the major pathogen causing fatal neurological complications of hand, foot, and mouth disease (HFMD) in young children. Currently no effective antiviral therapy is available. In the present study, we found that natural compound Berberine (BBR) displayed potent inhibitory effe...