Berberine prevents lethal EV71 neurological infection in newborn mice

• Κύριοι συγγραφείς: Guangyi Cui (Συγγραφέας), Han Wang (Συγγραφέας), Chongting Yang (Συγγραφέας), Xiaoxiao Zhou (Συγγραφέας), Junyi Wang (Συγγραφέας), Tong Wang (Συγγραφέας), Tonghui Ma (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Enterovirus 71 (EV71) is the major pathogen causing fatal neurological complications of hand, foot, and mouth disease (HFMD) in young children. Currently no effective antiviral therapy is available. In the present study, we found that natural compound Berberine (BBR) displayed potent inhibitory effe...