Adaptive Immunity and Antigen-Specific Activation in Obesity-Associated Insulin Resistance

• 主要な著者: Melissa Hui Yen Chng (著者), Michael N. Alonso (著者), Sarah E. Barnes (著者), Khoa D. Nguyen (著者), Edgar G. Engleman (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2015-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Type 2 diabetes mellitus (T2D) is a metabolic disease that is strongly tied to obesity and often preceded by insulin resistance (IR). It has been established that chronic inflammation of hypertrophic adipose tissue depots in obese individuals leads to obesity-associated IR and is mediated by cells o...