Phenotyping Indices of CYP450 and P-Glycoprotein in Human Volunteers and in Patients Treated with Painkillers or Psychotropic Drugs

• Váldodahkkit: Léa Darnaud (Dahkki), Clément Delage (Dahkki), Youssef Daali (Dahkki), Anne-Priscille Trouvin (Dahkki), Serge Perrot (Dahkki), Nihel Khoudour (Dahkki), Nadia Merise (Dahkki), Laurence Labat (Dahkki), Bruno Etain (Dahkki), Frank Bellivier (Dahkki), Célia Lloret-Linares (Dahkki), Vanessa Bloch (Dahkki), Emmanuel Curis (Dahkki), Xavier Declèves (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2023-03-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Drug-metabolizing enzymes and drug transporters are key determinants of drug pharmacokinetics and response. The cocktail-based cytochrome P450 (CYP) and drug transporter phenotyping approach consists in the administration of multiple CYP or transporter-specific probe drugs to determine their activit...