IFN-γ in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis

• Main Authors: Hui Zheng (Author), Xiaolin Guan (Author), Xin Meng (Author), Ying Tong (Author), Yanchun Wang (Author), Suhong Xie (Author), Lin Guo (Author), Renquan Lu (Author)
• Format: Book
• Published: BMC, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Inflammation and immunity are two main characteristics of tumor microenvironment (TME). Interferon-gamma (IFN-γ) is generally considered as a pro-inflammatory cytokine which mediates anti-tumor immune response. Recently, IFN-γ was also reported to play a protumorigenic role. Howe...