hmSOD1 gene mutation‐induced disturbance in iron metabolism is mediated by impairment of Akt signalling pathway

• मुख्य लेखकों: Malgorzata Halon‐Golabek (लेखक), Andzelika Borkowska (लेखक), Jan J. Kaczor (लेखक), Wieslaw Ziolkowski (लेखक), Damian J. Flis (लेखक), Narcyz Knap (लेखक), Kajetan Kasperuk (लेखक), Jedrzej Antosiewicz (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2018-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Recently, skeletal muscle atrophy, impairment of iron metabolism, and insulin signalling have been reported in rats suffering from amyotrophic lateral sclerosis (ALS). However, the interrelationship between these changes has not been studied. We hypothesize that an impaired Akt-F...