hmSOD1 gene mutation‐induced disturbance in iron metabolism is mediated by impairment of Akt signalling pathway

• প্রধান লেখক: Malgorzata Halon‐Golabek (লেখক), Andzelika Borkowska (লেখক), Jan J. Kaczor (লেখক), Wieslaw Ziolkowski (লেখক), Damian J. Flis (লেখক), Narcyz Knap (লেখক), Kajetan Kasperuk (লেখক), Jedrzej Antosiewicz (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2018-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background Recently, skeletal muscle atrophy, impairment of iron metabolism, and insulin signalling have been reported in rats suffering from amyotrophic lateral sclerosis (ALS). However, the interrelationship between these changes has not been studied. We hypothesize that an impaired Akt-F...