Cav3.2-dependent hyperalgesia/allodynia following intrathecal and intraplantar zinc chelator administration in rodents

• मुख्य लेखकों: Shiori Tomita (लेखक), Fumiko Sekiguchi (लेखक), Katsuki Naoe (लेखक), Shiyu Shikimi (लेखक), Yoshihito Kasanami (लेखक), Maya Ohigashi (लेखक), Maho Tsubota (लेखक), Atsufumi Kawabata (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Cav3.2, a T-type calcium channel (T-channel) family member, is expressed in the nociceptors and spinal cord, and its activity is largely suppressed by zinc under physiological conditions. In rats, intrathecal and intraplantar administration of a zinc chelator, TPEN, caused T-channel-dependent mechan...