Selection and verification of antibodies against the cytoplasmic domain of M2 of influenza, a transmembrane protein

• Main Authors: Nileena Velappan (Author), Sofiya Micheva-Viteva (Author), Samantha H. Adikari (Author), Geoffrey S. Waldo (Author), Antonietta M. Lillo (Author), Andrew R.M. Bradbury (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interactions between the cytoplasmic domains of viral transmembrane proteins and host machinery often determine the outcome of viral infection. The M2 protein of influenza A has been identified as a key player in autophagy-mediated viral replication. Here, we describe the engineering and validation...