Selection and verification of antibodies against the cytoplasmic domain of M2 of influenza, a transmembrane protein

• Hauptverfasser: Nileena Velappan (Verfasst von), Sofiya Micheva-Viteva (Verfasst von), Samantha H. Adikari (Verfasst von), Geoffrey S. Waldo (Verfasst von), Antonietta M. Lillo (Verfasst von), Andrew R.M. Bradbury (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Interactions between the cytoplasmic domains of viral transmembrane proteins and host machinery often determine the outcome of viral infection. The M2 protein of influenza A has been identified as a key player in autophagy-mediated viral replication. Here, we describe the engineering and validation...