Modeling an Optimal 3D Skin-on-Chip within Microfluidic Devices for Pharmacological Studies

• Main Authors: Estibaliz Fernandez-Carro (Author), Maricke Angenent (Author), Tamara Gracia-Cazaña (Author), Yolanda Gilaberte (Author), Clara Alcaine (Author), Jesús Ciriza (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Preclinical research remains hampered by an inadequate representation of human tissue environments which results in inaccurate predictions of a drug candidate's effects and target's suitability. While human 2D and 3D cell cultures and organoids have been extensively improved to mimic the p...