Modeling an Optimal 3D Skin-on-Chip within Microfluidic Devices for Pharmacological Studies

• Glavni autori: Estibaliz Fernandez-Carro (Autor), Maricke Angenent (Autor), Tamara Gracia-Cazaña (Autor), Yolanda Gilaberte (Autor), Clara Alcaine (Autor), Jesús Ciriza (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2022-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Preclinical research remains hampered by an inadequate representation of human tissue environments which results in inaccurate predictions of a drug candidate's effects and target's suitability. While human 2D and 3D cell cultures and organoids have been extensively improved to mimic the p...