Virtual Cocrystal Screening of Adefovir Dipivoxyl: Identification of New Solid Forms with Improved Dissolution and Permeation Profiles
The application of a computational screening methodology based on the calculation of intermolecular interaction energies has guided the discovery of new multicomponent solid forms of the oral antiviral Adefovir Dipivoxyl. Three new cocrystals with resorcinol, orcinol and hydroquinone have been synth...
Saved in:
Main Authors: | Rafael Barbas (Author), Hanan Fael (Author), Samuel Lee (Author), Rebeca Ruiz (Author), Christopher A. Hunter (Author), Elisabet Fuguet (Author), Clara Ràfols (Author), Rafel Prohens (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2022-10-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Synthesis and Characterization of a New Norfloxacin/Resorcinol Cocrystal with Enhanced Solubility and Dissolution Profile
by: Hanan Fael, et al.
Published: (2021) -
Dissolution rate of ciprofloxacin and its cocrystal with resorcinol
by: Clara Ràfols, et al.
Published: (2018) -
Computational screens can speed up the discovery of pharmaceutical cocrystals
by: Rafel Prohens, et al.
Published: (2018) -
Solid State Characterization and Dissolution Enhancement of Nevirapine Cocrystals
by: Prabhakar Panzade, et al.
Published: (2021) -
Evaluation of Ion-pair Formation of Adefovir to Improve Permeation across Artificial and Biological Membranes
by: Bahar Darsazan, et al.
Published: (2018)