ZG16 promotes T-cell mediated immunity through direct binding to PD-L1 in colon cancer

• Glavni autori: Hui Meng (Autor), Wu Yao (Autor), Yuhui Yin (Autor), Yizhen Li (Autor), Yi Ding (Autor), Liang Wang (Autor), Mingzhi Zhang (Autor)
• Format: Knjiga
• Izdano: BMC, 2022-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Immunotherapy using programmed cell death 1 (PD1) inhibitors has shown great efficacy in colorectal cancer patients harboring mismatch-repair-deficient (dMMR) and microsatellite instability-high (MSI-H) alterations. We previously showed a negative correlation of zymogen granule protein 16 (...