ZG16 promotes T-cell mediated immunity through direct binding to PD-L1 in colon cancer

• Main Authors: Hui Meng (Author), Wu Yao (Author), Yuhui Yin (Author), Yizhen Li (Author), Yi Ding (Author), Liang Wang (Author), Mingzhi Zhang (Author)
• Format: Book
• Published: BMC, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Immunotherapy using programmed cell death 1 (PD1) inhibitors has shown great efficacy in colorectal cancer patients harboring mismatch-repair-deficient (dMMR) and microsatellite instability-high (MSI-H) alterations. We previously showed a negative correlation of zymogen granule protein 16 (...