Unveiling the Role of Tryptophan 2,3-Dioxygenase in the Angiogenic Process

• Auteurs principaux: Marta Cecchi (Auteur), Cecilia Anceschi (Auteur), Angela Silvano (Auteur), Maria Luisa Coniglio (Auteur), Aurora Chinnici (Auteur), Lucia Magnelli (Auteur), Andrea Lapucci (Auteur), Anna Laurenzana (Auteur), Astrid Parenti (Auteur)
• Format: Livre
• Publié: MDPI AG, 2024-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background: Indoleamine 2,3-dioxygenase (IDO1) and tryptophan-2,3-dioxygenase (TDO) are the two principals enzymes involved in the catabolization of tryptophan (Trp) into kynurenine (Kyn). Despite their well-established role in the immune escape, their involvement in angiogenesis remains uncertain....