Unveiling the Role of Tryptophan 2,3-Dioxygenase in the Angiogenic Process

• Main Authors: Marta Cecchi (Author), Cecilia Anceschi (Author), Angela Silvano (Author), Maria Luisa Coniglio (Author), Aurora Chinnici (Author), Lucia Magnelli (Author), Andrea Lapucci (Author), Anna Laurenzana (Author), Astrid Parenti (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Indoleamine 2,3-dioxygenase (IDO1) and tryptophan-2,3-dioxygenase (TDO) are the two principals enzymes involved in the catabolization of tryptophan (Trp) into kynurenine (Kyn). Despite their well-established role in the immune escape, their involvement in angiogenesis remains uncertain....