Synthesis, Antibacterial Evaluation and QSAR of α-Substituted-N4-Acetamides of Ciprofloxacin and Norfloxacin

Synthesis, Antibacterial Evaluation and QSAR of α-Substituted-N4-Acetamides of Ciprofloxacin and Norfloxacin

Twenty six α-substituted N4-acetamide derivatives of ciprofloxacin (CIPRO) and norfloxacin (NOR) were synthesized and assayed for antibacterial activity against Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Bacillus subtilis. The derivatives were primarily more active against G...

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Main Authors: Amjad M. Qandil (Author), Lorca O. Al-Zoubi (Author), Amal G. Al-Bakri (Author), Haneen A. Amawi (Author), Qosay A. Al-Balas (Author), Abdulmalik M. Alkatheri (Author), Abdulkareem M. Albekairy (Author)
Format: Book
Published: MDPI AG, 2014-06-01T00:00:00Z.
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