Antibody-epitope conjugates deliver immunogenic T-cell epitopes more efficiently when close to cell surfaces

• मुख्य लेखकों: W. van der Wulp (लेखक), W. Luu (लेखक), M. E. Ressing (लेखक), J. Schuurman (लेखक), S. I. van Kasteren (लेखक), L. Guelen (लेखक), R. C. Hoeben (लेखक), B. Bleijlevens (लेखक), M. H. M. Heemskerk (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

ABSTRACTAntibody-mediated delivery of immunogenic viral CD8+ T-cell epitopes to redirect virus-specific T cells toward cancer cells is a promising new therapeutic avenue to increase the immunogenicity of tumors. Multiple strategies for viral epitope delivery have been shown to be effective. So far,...