Novel H7N9 influenza immunogen design enhances mobilization of seasonal influenza T cell memory in H3N2 pre-immune mice

• मुख्य लेखकों: Leonard Moise (लेखक), Lauren M. Meyers (लेखक), Hyesun Jang (लेखक), Mayara Grizotte-Lake (लेखक), Christine M. Boyle (लेखक), Bethany McGonnigal (लेखक), Pan Ge (लेखक), Ted M. Ross (लेखक), Anne S. De Groot (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2022-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Strategies that improve influenza vaccine immunogenicity are critical for the development of vaccines for pandemic preparedness. Hemagglutinin (HA)-specific CD4+ T cell epitopes support protective B cell responses against seasonal influenza. However, in the case of avian H7N9, which poses a pandemic...