In vitro and in vivo evaluation of macromolecular prodrug GC-FUA based nanoparticle for hepatocellular carcinoma chemotherapy

• Autors principals: Can Huang (Autor), Na-Mei Li (Autor), Pei Gao (Autor), Sa Yang (Autor), Qian Ning (Autor), Wen Huang (Autor), Zhi-Ping Li (Autor), Peng-Ju Ye (Autor), Li Xiang (Autor), Dong-Xiu He (Autor), Xiang-Wen Tan (Autor), Cui-Yun Yu (Autor)
• Format: Llibre
• Publicat: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

A novel type of macromolecular prodrug delivery system is reported in this research. The N-galactosylated-chitosan-5-fluorouracil acetic acid conjugate (GC-FUA) based nanoparticle delivery system was evaluated in vitro and in vivo. Biocompatibility of GC-FUA-NPs was screened by BSA adsorption test a...