Novel Use of PLGA Microspheres to Create an Animal Model of Glaucoma with Progressive Neuroretinal Degeneration

• Главные авторы: David Garcia-Herranz (Автор), Maria Jesus Rodrigo (Автор), Manuel Subias (Автор), Teresa Martinez-Rincon (Автор), Silvia Mendez-Martinez (Автор), Irene Bravo-Osuna (Автор), Aina Bonet (Автор), Jesus Ruberte (Автор), Julian Garcia-Feijoo (Автор), Luis Pablo (Автор), Elena Garcia-Martin (Автор), Rocío Herrero-Vanrell (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2021-02-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Progressive degeneration of neuroretinal tissue with maintained elevated intraocular pressure (IOP) to simulate chronic glaucoma was produced by intracameral injections of poly (lactic-co-glycolic) acid (PLGA) microspheres (Ms) in rat eyes. The right eye of 39 rats received different sizes of PLGA-M...