Novel Use of PLGA Microspheres to Create an Animal Model of Glaucoma with Progressive Neuroretinal Degeneration

• Egile Nagusiak: David Garcia-Herranz (Egilea), Maria Jesus Rodrigo (Egilea), Manuel Subias (Egilea), Teresa Martinez-Rincon (Egilea), Silvia Mendez-Martinez (Egilea), Irene Bravo-Osuna (Egilea), Aina Bonet (Egilea), Jesus Ruberte (Egilea), Julian Garcia-Feijoo (Egilea), Luis Pablo (Egilea), Elena Garcia-Martin (Egilea), Rocío Herrero-Vanrell (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2021-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Progressive degeneration of neuroretinal tissue with maintained elevated intraocular pressure (IOP) to simulate chronic glaucoma was produced by intracameral injections of poly (lactic-co-glycolic) acid (PLGA) microspheres (Ms) in rat eyes. The right eye of 39 rats received different sizes of PLGA-M...