Design of multi-epitope peptides containing HLA class-I and class-II-restricted epitopes derived from immunogenic Leishmania proteins, and evaluation of CD4+ and CD8+ T cell responses induced in cured cutaneous leishmaniasis subjects.

• Päätekijät: Sarra Hamrouni (Tekijä), Rachel Bras-Gonçalves (Tekijä), Abdelhamid Kidar (Tekijä), Karim Aoun (Tekijä), Rym Chamakh-Ayari (Tekijä), Elodie Petitdidier (Tekijä), Yasmine Messaoudi (Tekijä), Julie Pagniez (Tekijä), Jean-Loup Lemesre (Tekijä), Amel Meddeb-Garnaoui (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Public Library of Science (PLoS), 2020-03-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Human leishmaniasis is a public health problem worldwide for which the development of a vaccine remains a challenge. T cell-mediated immune responses are crucial for protection. Peptide vaccines based on the identification of immunodominant T cell epitopes able to induce T cell specific immune respo...