Stemness-Attenuating miR-503-3p as a Paracrine Factor to Regulate Growth of Cancer Stem Cells

• Príomhchruthaitheoirí: Minkoo Seo (Údar), Seung Min Kim (Údar), Eun Young Woo (Údar), Ki-Cheol Han (Údar), Eun Joo Park (Údar), Seongyeol Ko (Údar), Eun wook Choi (Údar), Mihue Jang (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Hindawi Limited, 2018-01-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Cancer stem cells (CSCs) with self-renewal abilities endorse cellular heterogeneity, resulting in metastasis and recurrence. However, there are no promising therapeutics directed against CSCs. Herein, we found that miR-503-3p inhibited tumor growth via the regulation of CSC proliferation and self-re...