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Up-regulation of ABCG1 is associated with methotrexate resistance in acute lymphoblastic leukemia cells

Acute lymphoblastic leukemia (ALL) is a prevalent hematologic malignancy in children, and methotrexate (MTX) is a widely employed curative treatment. Despite its common use, clinical resistance to MTX is frequently encountered. In this study, an MTX-resistant cell line (Reh-MTXR) was established thr...

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Bibliographic Details
Main Authors:	Yao Chen (Author), Houshun Fang (Author), Huiying Sun (Author), Xiaoyu Wu (Author), Yan Xu (Author), Bin-Bing S. Zhou (Author), Hui Li (Author)
Format:	Book
Published:	Frontiers Media S.A., 2024-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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