Stability study on an anti-cancer drug 4-(3,5-bis(2-chlorobenzylidene)-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid (CLEFMA) using a stability-indicating HPLC method

CLEFMA, 4-(3,5-bis(2-chlorobenzylidene)-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid, is a new chemical entity with anti-cancer and anti-inflammatory activities. Here, we report its stability in solution against stress conditions of exposure to acid/base, light, oxidant, high temperature, and plasma...

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Main Authors: Dhawal Raghuvanshi (Author), Gregory Nkepang (Author), Alamdar Hussain (Author), Hooman Yari (Author), Vibhudutta Awasthi (Author)
Format: Book
Published: Elsevier, 2017-02-01T00:00:00Z.
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