Stability study on an anti-cancer drug 4-(3,5-bis(2-chlorobenzylidene)-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid (CLEFMA) using a stability-indicating HPLC method

• Autori principali: Dhawal Raghuvanshi (Autore), Gregory Nkepang (Autore), Alamdar Hussain (Autore), Hooman Yari (Autore), Vibhudutta Awasthi (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2017-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

CLEFMA, 4-(3,5-bis(2-chlorobenzylidene)-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid, is a new chemical entity with anti-cancer and anti-inflammatory activities. Here, we report its stability in solution against stress conditions of exposure to acid/base, light, oxidant, high temperature, and plasma...