Design, synthesis and molecular docking of novel diarylcyclohexenone and diarylindazole derivatives as tubulin polymerization inhibitors

New target compounds were designed as inhibitors of tubulin polymerization relying on using two types of ring B models (cyclohexenone and indazole) to replace the central ring in colchicine. Different functional groups (R1) were attached to manipulate their physicochemical properties and/or their bi...

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Bibliographic Details
Main Authors: Riham I. Ahmed (Author), Essam Eldin A. Osman (Author), Fadi M. Awadallah (Author), Samir M. El-Moghazy (Author)
Format: Book
Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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