Synthesis, Antimalarial, Antileishmanial, and Cytotoxicity Activities and Preliminary In Silico ADMET Studies of 2-(7-Chloroquinolin-4-ylamino)ethyl Benzoate Derivatives

• Asıl Yazarlar: Joyce E. Gutiérrez (Yazar), Hegira Ramírez (Yazar), Esteban Fernandez-Moreira (Yazar), María E. Acosta (Yazar), Michael R. Mijares (Yazar), Juan Bautista De Sanctis (Yazar), Soňa Gurská (Yazar), Petr Džubák (Yazar), Marián Hajdúch (Yazar), Liesangerli Labrador-Fagúndez (Yazar), Bruno G. Stella (Yazar), Luis José Díaz-Pérez (Yazar), Gustavo Benaim (Yazar), Jaime E. Charris (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

A series of heterocyclic chloroquine hybrids, containing a chain of two carbon atoms at position four of the quinolinic chain and acting as a link between quinoline and several benzoyl groups, is synthesized and screened in vitro as an inhibitor of β-hematin formation and in vivo for its antimalaria...