Omeprazole Prevents Colistin-Induced Nephrotoxicity in Rats: Emphasis on Oxidative Stress, Inflammation, Apoptosis and Colistin Accumulation in Kidneys

• 主要な著者: Mohammed Z. Nasrullah (著者), Khalid Eljaaly (著者), Thikryat Neamatallah (著者), Usama A. Fahmy (著者), Abdulmohsin J. Alamoudi (著者), Hussain T. Bakhsh (著者), Ashraf B. Abdel-Naim (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The clinical value of colistin, a polymyxin antibiotic, is limited by its nephrotoxicity. Omeprazole is a commonly prescribed proton pump inhibitor. The current study aimed to evaluate the effects of the concomitant administration of omeprazole on colistin-induced nephrotoxicity in rats. Omeprazole...