Effects of Angiotensin II Type 1A Receptor on ACE2, Neprilysin and KIM-1 in Two Kidney One Clip (2K1C) Model of Renovascular Hypertension

• Auteurs principaux: Laale F. Alawi (Auteur), Sanjeev Dhakal (Auteur), Sana E. Emberesh (Auteur), Harshal Sawant (Auteur), Anhar Hosawi (Auteur), Unmesha Thanekar (Auteur), Nadja Grobe (Auteur), Khalid M. Elased (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Activation of the renin angiotensin system plays a pivotal role in the regulation of blood pressure, which is mainly attributed to the formation of angiotensin-II (Ang II). The actions of Ang II are mediated through binding to the Ang-II type 1 receptor (AT1R) which leads to increased blood pressure...