Design, synthesis and antitumor activity of C3/C3 bis-fluoroquonolones cross-linked with [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazole

• Ngā kaituhi matua: Guo-qiang Hu (Author), Yong Yang (Author), Lei Yi (Author), Guo-qiang Wang (Author), Nan-nan Duan (Author), Xiao-yi Wen (Author), Tie-yao Cao (Author), Song-qiang Xie (Author), Wen-Long Huang (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2011-10-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

To contribute to the development of an efficient method for the conversion of antibacterial fluoroquinolones to antitumor fluoroquinolones, a series of C3/C3 bis-fluoroquinolone fused heterocycles cross-linked with a [1,2,4]-triazolo[3,4-b] [1,3,4]-thiadiazole core as a common bioisostere of two car...