Design, synthesis and antitumor activity of C3/C3 bis-fluoroquonolones cross-linked with [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazole

• Hoofdauteurs: Guo-qiang Hu (Auteur), Yong Yang (Auteur), Lei Yi (Auteur), Guo-qiang Wang (Auteur), Nan-nan Duan (Auteur), Xiao-yi Wen (Auteur), Tie-yao Cao (Auteur), Song-qiang Xie (Auteur), Wen-Long Huang (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2011-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

To contribute to the development of an efficient method for the conversion of antibacterial fluoroquinolones to antitumor fluoroquinolones, a series of C3/C3 bis-fluoroquinolone fused heterocycles cross-linked with a [1,2,4]-triazolo[3,4-b] [1,3,4]-thiadiazole core as a common bioisostere of two car...