Design, synthesis and antitumor activity of C3/C3 bis-fluoroquonolones cross-linked with [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazole

• Principais autores: Guo-qiang Hu (Autor), Yong Yang (Autor), Lei Yi (Autor), Guo-qiang Wang (Autor), Nan-nan Duan (Autor), Xiao-yi Wen (Autor), Tie-yao Cao (Autor), Song-qiang Xie (Autor), Wen-Long Huang (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2011-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

To contribute to the development of an efficient method for the conversion of antibacterial fluoroquinolones to antitumor fluoroquinolones, a series of C3/C3 bis-fluoroquinolone fused heterocycles cross-linked with a [1,2,4]-triazolo[3,4-b] [1,3,4]-thiadiazole core as a common bioisostere of two car...