Encapsulated Escitalopram and Paroxetine Intranasal Co-Administration: In Vitro/In Vivo Evaluation

• Главные авторы: Soraia Silva (Автор), Joana Bicker (Автор), Carla Fonseca (Автор), Nuno R. Ferreira (Автор), Carla Vitorino (Автор), Gilberto Alves (Автор), Amílcar Falcão (Автор), Ana Fortuna (Автор)
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• Опубликовано: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Предметы: article
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Depression is a common mental disorder. Its treatment with selective serotonin reuptake inhibitors (SSRIs) is effective only in a fraction of patients, and pharmacoresistance is increasing steadily. Intranasal (IN) drug delivery to the brain stands out as a promising strategy to improve current ther...