PK/PD modeling and simulation of the in vitro activity of the combinations of isavuconazole with echinocandins against Candida auris

• المؤلفون الرئيسيون: Unai Caballero (مؤلف), Elena Eraso (مؤلف), Guillermo Quindós (مؤلف), Valvanera Vozmediano (مؤلف), Stephan Schmidt (مؤلف), Nerea Jauregizar (مؤلف)
• التنسيق: كتاب
• منشور في: Wiley, 2023-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract In vitro combination of echinocandins and isavuconazole against the emerging species Candida auris is mainly synergistic. However, this combination has not been evaluated in clinical settings. A pharmacokinetic/pharmacodynamic modeling and simulation approach based on in vitro data may be h...